2
2
5
Cat. No. | Product Name | Target | Signaling Pathways |
---|---|---|---|
T35450 |
α-GalCer analog 8
α-GalCer analog 8,α-Galactosylceramide analog 8 |
||
α-Galactosylceramide analog 8 (α-GalCer analog 8) is a triazole derivative of α-galactosylceramide. [1] It increases IL-2 secretion by DN32.D3 NKT hybridoma cells when co-cultured with CD1d-transfected RBL cells pre-loaded with α-GalCer analog 8 at a concentration of 32 ng/ml. α-GalCer analog 8 (32 ng/ml) induces IL-4 secretion to a greater extent than the synthetic α-GalCer KRN 7000 in mouse splenocytes in vitro and in mouse serum following administration of a 1 µg per animal dose, indicati... | |||
T38008 | KBC-007 | ||
KBC-007 is a synthetic branched chain-containing analog of α-galactosylceramide (α-GalCer). It induces IL-4 and IFN-γ secretion by mouse splenocytes when used at a concentration of 0.5 ng/ml and IL-2 secretion by DN32.D3 NKT hybridoma cells co-cultured with CD1d-transfected RBL cells pre-loaded with KBC-007 at a concentration of 8 ng/ml. KBC-007 (1 μg per animal) increases levels of IL-4, but not IFN-γ, to a similar degree as α-GalCer in mouse serum. KBC-007 (0.5 μg per animal) increases the sur... |
Cat. No. | Product Name | Target | Signaling Pathways |
---|---|---|---|
T14193 |
α-Galactosylceramide
KRN7000,α-GalCer |
Others | Others |
α-Galactosylceramide (KRN7000) 是一种具有抗肿瘤和免疫刺激作用的合成糖脂。它是一种高效的 NKT 细胞激动剂,可与 CD1d 有效结合。它与 CD1d 的复合物可与 NKT 细胞的 T 细胞抗原受体结合。 | |||
T38285 |
C24:1 3'-sulfo Galactosylceramide (d18:1/24:1(15Z))
C24:1 3'-sulfo Galactosylceramide (d18:1/24:1(15Z)) |
Others | Others |
C24:1 3'-sulfo Galactosylceramide (d18:1/24:1(15Z))是成熟髓鞘中主要的硫酸盐类化合物。C24:1 3'-sulfo Galactosylceramide (d18:1/24:1(15Z)) 在大鼠小脑中发现活跃的髓发生鞘化反应时积累率高于C24 3'-sulfo 半乳糖甘油酰胺。C24:1 3'-sulfo Galactosylceramide (d18:1/24:1(15Z))与C 型凝集素和免疫球蛋白样受体相互作用使对LMIR5的亲和力高。C24:1 3'-sulfo Galactosylceramide (d18:1/24:1(15Z))诱导嗜碱细胞产生MCP-1,可通过增加LMIR5激活NFAT,但不能诱导肥大细胞 。C24:1 3'-sulfo Galactosylceramide (d18:1/24:1(15Z))在体外与CD1d 结合,并增加游离小鼠脾细胞的增殖。 |
Cat. No. | Product Name | Species | Expression System |
---|---|---|---|
TMPY-02854 |
CD1D & B2M Heterodimer Protein, Human, Recombinant (His)
CD1D & B2M Heterodimer |
Human | HEK293 Cells |
CD1D & B2M Heterodimer Protein, Human, Recombinant (His) is expressed in HEK293 mammalian cells with His tag. The predicted molecular weight is 45 kDa and the accession number is P15813&P61769. | |||
TMPY-01397 |
CD1D Protein, Mouse, Recombinant (His)
Cd1d,Cd1a,CD1d ... |
Mouse | HEK293 Cells |
CD1D Protein, Mouse, Recombinant (His) is expressed in HEK293 mammalian cells with His tag. The predicted molecular weight is 33.7 kDa and the accession number is A0A0R4J090. | |||
TMPY-04117 |
CD1D Protein, Mouse, Recombinant (His & hFc)
CD1.1,Cd1a,Cd1d,CD |
Mouse | HEK293 Cells |
CD1D Protein, Mouse, Recombinant (His & hFc) is expressed in HEK293 mammalian cells with His and hFc tag. The predicted molecular weight is 60.4 kDa and the accession number is A0A0R4J090. | |||
TMPY-05035 |
CD1D1 & B2M Heterodimer Protein, Mouse, Recombinant (His)
|
Mouse | HEK293 Cells |
CD1D1 & B2M Heterodimer Protein, Mouse, Recombinant (His) is expressed in HEK293 mammalian cells with His tag. The predicted molecular weight is 45.4 kDa and the accession number is NP_031665.2&P01887. | |||
TMPY-04741 |
CD1D2 & B2M Heterodimer Protein, Mouse, Recombinant (His)
CD1D2 & B2M |
Mouse | HEK293 Cells |
CD1D2 & B2M Heterodimer Protein, Mouse, Recombinant (His) is expressed in HEK293 mammalian cells with His tag. The predicted molecular weight is 45.4 kDa. |